Out of 303 ZIP codes with data in Missouri, these are the highest-ranked areas for pfas status. See also: National ZIP Codes with PFAS Detections in Water | All Missouri Rankings
| Statistic | Value |
|---|---|
| ZIP codes ranked | 303 |
| Highest value | 0.1 ppt |
| Median value | 0.0 ppt |
| State | Missouri |
Top 100 Worst ZIP Codes
| Rank | ZIP Code | City | State | PFAS Status | Safety Score |
|---|---|---|---|---|---|
| 1 | 63401 | Hannibal | MO | 0.1 ppt | — |
| 2 | 63459 | New London | MO | 0.1 ppt | — |
| 3 | 63461 | Palmyra | MO | 0.1 ppt | — |
| 4 | 65559 | Saint James | MO | 0.0 ppt | — |
| 5 | 63019 | Crystal City | MO | 0.0 ppt | 78/100 |
| 6 | 64632 | Cainsville | MO | 0.0 ppt | — |
| 7 | 64661 | Mercer | MO | 0.0 ppt | — |
| 8 | 64673 | Princeton | MO | 0.0 ppt | — |
| 9 | 63701 | Cape Girardeau | MO | 0.0 ppt | — |
| 10 | 63703 | Cape Girardeau | MO | 0.0 ppt | — |
| 11 | 63755 | Jackson | MO | 0.0 ppt | — |
| 12 | 63780 | Scott City | MO | 0.0 ppt | — |
| 13 | 63430 | Alexandria | MO | 0.0 ppt | — |
| 14 | 63432 | Arbela | MO | 0.0 ppt | — |
| 15 | 63465 | Revere | MO | 0.0 ppt | — |
| 16 | 63536 | Downing | MO | 0.0 ppt | — |
| 17 | 63543 | Gorin | MO | 0.0 ppt | — |
| 18 | 63555 | Memphis | MO | 0.0 ppt | — |
| 19 | 63561 | Queen City | MO | 0.0 ppt | — |
| 20 | 63563 | Rutledge | MO | 0.0 ppt | — |
| 21 | 65584 | Saint Robert | MO | 0.0 ppt | — |
| 22 | 63352 | Laddonia | MO | 0.0 ppt | — |
| 23 | 63382 | Vandalia | MO | 0.0 ppt | — |
| 24 | 63436 | Center | MO | 0.0 ppt | — |
| 25 | 63441 | Frankford | MO | 0.0 ppt | — |
| 26 | 63443 | Hunnewell | MO | 0.0 ppt | — |
| 27 | 63456 | Monroe City | MO | 0.0 ppt | 80/100 |
| 28 | 63462 | Perry | MO | 0.0 ppt | 81/100 |
| 29 | 65275 | Paris | MO | 0.0 ppt | 81/100 |
| 30 | 65283 | Stoutsville | MO | 0.0 ppt | 81/100 |
| 31 | 63330 | Annada | MO | 0.0 ppt | — |
| 32 | 63334 | Bowling Green | MO | 0.0 ppt | — |
| 33 | 63336 | Clarksville | MO | 0.0 ppt | — |
| 34 | 63339 | Curryville | MO | 0.0 ppt | — |
| 35 | 63344 | Eolia | MO | 0.0 ppt | — |
| 36 | 63353 | Louisiana | MO | 0.0 ppt | — |
| 37 | 63359 | Middletown | MO | 0.0 ppt | — |
| 38 | 63438 | Durham | MO | 0.0 ppt | — |
| 39 | 63440 | Ewing | MO | 0.0 ppt | — |
| 40 | 63448 | La Grange | MO | 0.0 ppt | — |
| 41 | 63454 | Maywood | MO | 0.0 ppt | — |
| 42 | 63463 | Philadelphia | MO | 0.0 ppt | — |
| 43 | 63471 | Taylor | MO | 0.0 ppt | — |
| 44 | 63376 | Saint Peters | MO | 0.0 ppt | 65/100 |
| 45 | 65020 | Camdenton | MO | 0.0 ppt | — |
| 46 | 64741 | Deerfield | MO | 0.0 ppt | — |
| 47 | 64423 | Barnard | MO | 0.0 ppt | — |
| 48 | 64427 | Bolckow | MO | 0.0 ppt | 64/100 |
| 49 | 64428 | Burlington Junction | MO | 0.0 ppt | — |
| 50 | 64431 | Clearmont | MO | 0.0 ppt | — |
| 51 | 64434 | Conception Junction | MO | 0.0 ppt | — |
| 52 | 64445 | Elmo | MO | 0.0 ppt | — |
| 53 | 64455 | Graham | MO | 0.0 ppt | — |
| 54 | 64457 | Guilford | MO | 0.0 ppt | — |
| 55 | 64461 | Hopkins | MO | 0.0 ppt | — |
| 56 | 64466 | Maitland | MO | 0.0 ppt | — |
| 57 | 64468 | Maryville | MO | 0.0 ppt | — |
| 58 | 64475 | Parnell | MO | 0.0 ppt | — |
| 59 | 64476 | Pickering | MO | 0.0 ppt | — |
| 60 | 64479 | Ravenwood | MO | 0.0 ppt | — |
| 61 | 64486 | Sheridan | MO | 0.0 ppt | — |
| 62 | 64487 | Skidmore | MO | 0.0 ppt | — |
| 63 | 64489 | Stanberry | MO | 0.0 ppt | — |
| 64 | 64001 | Alma | MO | 0.0 ppt | — |
| 65 | 64020 | Concordia | MO | 0.0 ppt | — |
| 66 | 64021 | Corder | MO | 0.0 ppt | — |
| 67 | 64037 | Higginsville | MO | 0.0 ppt | — |
| 68 | 64067 | Lexington | MO | 0.0 ppt | — |
| 69 | 64071 | Mayview | MO | 0.0 ppt | — |
| 70 | 64076 | Odessa | MO | 0.0 ppt | — |
| 71 | 65321 | Blackburn | MO | 0.0 ppt | — |
| 72 | 65339 | Malta Bend | MO | 0.0 ppt | — |
| 73 | 65351 | Sweet Springs | MO | 0.0 ppt | — |
| 74 | 63031 | Florissant | MO | 0.0 ppt | 83/100 |
| 75 | 63050 | Hillsboro | MO | 0.0 ppt | 78/100 |
| 76 | 63090 | Washington | MO | 0.0 ppt | — |
| 77 | 63109 | Saint Louis | MO | 0.0 ppt | 70/100 |
| 78 | 63341 | Defiance | MO | 0.0 ppt | 83/100 |
| 79 | 63368 | O Fallon | MO | 0.0 ppt | 83/100 |
| 80 | 63534 | Callao | MO | 0.0 ppt | — |
| 81 | 63558 | New Cambria | MO | 0.0 ppt | — |
| 82 | 63640 | Farmington | MO | 0.0 ppt | — |
| 83 | 63670 | Sainte Genevieve | MO | 0.0 ppt | 80/100 |
| 84 | 64015 | Blue Springs | MO | 0.0 ppt | 61/100 |
| 85 | 64117 | Kansas City | MO | 0.0 ppt | 61/100 |
| 86 | 64118 | Kansas City | MO | 0.0 ppt | 62/100 |
| 87 | 64131 | Kansas City | MO | 0.0 ppt | 64/100 |
| 88 | 64134 | Kansas City | MO | 0.0 ppt | 64/100 |
| 89 | 64658 | Marceline | MO | 0.0 ppt | — |
| 90 | 65010 | Ashland | MO | 0.0 ppt | 82/100 |
| 91 | 65201 | Columbia | MO | 0.0 ppt | 79/100 |
| 92 | 65202 | Columbia | MO | 0.0 ppt | 79/100 |
| 93 | 65203 | Columbia | MO | 0.0 ppt | 80/100 |
| 94 | 65230 | Armstrong | MO | 0.0 ppt | — |
| 95 | 65243 | Clark | MO | 0.0 ppt | — |
| 96 | 65244 | Clifton Hill | MO | 0.0 ppt | — |
| 97 | 65247 | Excello | MO | 0.0 ppt | — |
| 98 | 65248 | Fayette | MO | 0.0 ppt | — |
| 99 | 65254 | Glasgow | MO | 0.0 ppt | — |
| 100 | 65255 | Hallsville | MO | 0.0 ppt | 77/100 |
Methodology
PFAS detection data comes from EPA UCMR5 monitoring, state-level testing programs, and Consumer Confidence Reports. ZIP codes are ranked by maximum PFAS concentration detected. The EPA has set MCLs of 4 ppt for PFOA and PFOS individually. PFAS are persistent chemicals that do not break down in the environment.
Data sources: EPA Safe Drinking Water Information System (SDWIS), FEMA National Flood Insurance Program, EPA radon zone maps, EIA electricity rates, and Consumer Confidence Reports. Last updated: 2026-08-31.
Frequently Asked Questions
What are PFAS?
PFAS (per- and polyfluoroalkyl substances) are synthetic chemicals used in non-stick coatings, firefighting foam, and food packaging since the 1940s. They are called "forever chemicals" because they do not break down naturally. PFAS are linked to cancer, liver damage, thyroid disease, and immune system suppression.
How can I remove PFAS from my water?
Reverse osmosis (RO) and granular activated carbon (GAC) filters are effective at removing most PFAS from drinking water. NSF/ANSI 53 or 58 certified filters are recommended. Boiling water does NOT remove PFAS.
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